DIVERSITY Organoid Catalogue

In our DIVERSITY organoid catalogue, we have compiled a list of locally available PDO (Patient-Derived Organoid) models from our partner research institutes in Singapore. These models are accessible to the cancer research community and STCC collaborators.

DIVERSITY organoid catalogue

Breast

ID	Primary site	Collection site	Gender	Donor age	Clinical info	H&E	WES	WGS	RNA-seq	IHC	other assays	FFPE block
STCC-BRCA-001	Breast	Breast	F	63	✓	✓	-	-	-	✓	-	✓
STCC-BRCA-002	Breast	Brain	F	56	✓	✓	-	-	-	✓	-	✓
STCC-BRCA-003	Breast	Breast	F	83	✓	✓	-	-	-	-	-	✓
STCC-BRCA-004	Breast	Breast	F	85	✓	✓	-	-	-	✓	-	✓
STCC-BRCA-005	Breast	PE	F	40	✓	✓	-	-	-	✓	-	✓
STCC-BRCA-006	Breast	Breast	F	30	✓	✓	-	-	-	✓	-	✓
STCC-BRCA-007	Breast	PE	F	78	✓	✓	-	-	-	-	-	✓
STCC-BRCA-008	Breast	Breast	F	40	✓	✓	-	-	-	-	-	✓
Abbreviations: PE - Pleural Effusion, M - Male, F - Female, H&E - Haematoxylin and Eosin, WES - Whole Exome Sequencing, WGS - Whole Genome Sequencing, RNA-seq - RNA sequencing, IHC - Immunohistochemistry, FFPE - Formalin-Fixed Paraffin-Embedded

Colorectal

ID	Primary site	Collection site	Gender	Donor age	Clinical info	H&E	WES	WGS	RNA-seq	IHC	other assays	FFPE block
STCC-CRC-001	Colon	Liver	F	61	✓	✓	-	-	-	✓	-	✓
STCC-CRC-002	Colon	Colon	M	45	✓	-	✓	✓	✓	-	✓	-
STCC-CRC-003	Colon	Colon	F	41	✓	✓	✓	-	-	✓	-	✓
STCC-CRC-004	Colon	Colon	F	73	✓	✓	✓	-	-	✓	-	✓
STCC-CRC-005	Rectum	Rectum	F	47	✓	✓	✓	-	-	✓	-	✓
STCC-CRC-006	Colon	Ovary	F	41	✓	✓	✓	-	-	✓	-	✓
STCC-CRC-007	Colon	Ovary	F	73	✓	✓	✓	-	-	✓	-	✓
STCC-CRC-008	Rectum	Liver	F	47	✓	✓	✓	-	-	✓	-	✓
Abbreviations: M - Male, F - Female, H&E - Haematoxylin and Eosin, WES - Whole Exome Sequencing, WGS - Whole Genome Sequencing, RNA-seq - RNA sequencing, IHC - Immunohistochemistry, FFPE - Formalin-Fixed Paraffin-Embedded

Gastric

ID	Primary site	Collection site	Gender	Donor age	Clinical info	H&E	WES	WGS	RNA-seq	IHC	other assays	FFPE block
STCC-GS-001	Stomach	Stomach	M	60	✓	✓	✓	✓	✓	✓	✓	✓
STCC-GS-002	Stomach	Stomach	M	40	✓	-	✓	✓	✓	✓	✓	✓
STCC-GS-003	Stomach	Stomach	F	68	✓	-	✓	✓	✓	✓	✓	✓
STCC-GS-004	Stomach	Stomach	M	63	✓	-	✓	✓	✓	✓	✓	✓
STCC-GS-005	Stomach	Stomach	M	58	✓	✓	✓	✓	✓	✓	✓	✓
STCC-GS-006	Stomach	Stomach	M	81	✓	-	-	-	-	-	-	-
STCC-GS-007	Stomach	Stomach	M	47	✓	-	✓	✓	✓	✓	✓	-
STCC-GS-008	Stomach	Liver	F	46	✓	✓	✓	✓	✓	✓	✓	✓
STCC-GS-009	Stomach	Stomach	M	59	✓	✓	-	-	✓	-	-	✓
STCC-GS-010	GEJ	GEJ	M	59	✓	✓	✓	✓	✓	✓	✓	✓
STCC-GS-011	Stomach	Stomach	M	33	✓	✓	✓	✓	✓	✓	✓	✓
STCC-GS-012	Stomach	Stomach	M	52	✓	-	✓	✓	✓	✓	✓	-
STCC-GS-013	Stomach	Stomach	F	69	✓	-	✓	✓	-	✓	✓	-
Abbreviations: GEJ - Gastroesophageal Junction, M - Male, F - Female, H&E - Haematoxylin and Eosin, WES - Whole Exome Sequencing, WGS - Whole Genome Sequencing, RNA-seq - RNA sequencing, IHC - Immunohistochemistry, FFPE - Formalin-Fixed Paraffin-Embedded

Other

Cancer type	ID	Primary site	Collection site	Gender	Donor age	Clinical info	H&E	WES	WGS	RNA-seq	IHC	other assays	FFPE block
Cholangio	STCC-CCA-001	-	-	-	-	-	✓	-	-	-	✓	-	✓
Gallbladder Neuroendocrine	STCC-GB-001	Gallbladder	Gallbladder	F	65	✓	✓	-	-	-	✓	-	✓
Pancreatic	STCC-PDAC-001	Pancreas	Pancreas	F	77	✓	✓	-	-	-	-	-	✓
Pancreatic	STCC-PDAC-002	Pancreas	Pancreas	F	61	✓	✓	✓	-	-	✓	-	✓
Abbreviations: M - Male, F - Female, H&E - Haematoxylin and Eosin, WES - Whole Exome Sequencing, WGS - Whole Genome Sequencing, RNA-seq - RNA sequencing, IHC - Immunohistochemistry, FFPE - Formalin-Fixed Paraffin-Embedded

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