February 25, 2022
Platform Lead, Translational Research Integration & Support, Singapore Translational Cancer Consortium;
Senior Group Leader, Translational Research, Genomic Institute of Singapore
Dr Alexander Lezhava assumed the appointment as Group Leader, in the Translational Research group 1 (TR1), at the Genome Institute of Singapore, in August 2013. As a Senior Group Leader, Dr Lezhava, leads TR1 in promoting the smooth transition from basic research to advances in science and technology, and hence to innovation. Mainly focusing on molecular diagnostics, the mission of TR1 is to provide and market molecular diagnostic discoveries aligned with the industry needs and further develop these together with commercial partners.
Dr Lezhava also holds a concurrent appointment as the Program Director of POLARIS (Transforming Disease Management through Personalised Profiling) program since October 2016. He has actively pushed POLARIS to new heights in RIE2020. His key missions are for POLARIS to maintain its CAP accreditation on top of forging closer links with genomic initiatives at A*STAR as well as industry partners. POLARIS has become a supportive platform for clinical decision-making through molecular genomics. It has gradually evolved and is currently fully capable to serve a clinical community across Singapore and SEA region. In addition, Dr Lezhava serves the institute as a Management Representative for ISO accredited research groups for several years. Under his leadership, both TR1 and the New Generation Sequencing groups achieved ISO 13485 accreditation since 2015. This now has further expand with 2 additional research groups.
In response to the recent COVID-19 pandemic, A*STAR was commissioned for a central testing facility, where Dr Lezhava undertook the critical role of Laboratory Director of Stronghold Diagnostic Lab. His many years of experience managing POLARIS paired with his deep knowledge of molecular diagnostics renders him fit for this role.
Finally, Dr Lezhava extends his research network through his assignment as Visiting Professor of Academician of N. Kipshidze Central University Clinic, Tbilisi Georgia since 2008 and Visiting Professor of Clinical Research, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan, from 2010 to 2012. This enables the coveted exchange of both students and knowledge which is advantageous and enriching.
Prior to his current appointment, Dr Lezhava was a Research Director with Dx Assays from 2011 to 2013. His other earlier positions were a Senior Scientist followed by a Unit Leader under RIKEN, Japan from 2006 to 2010. He started out as a Senior Researcher with K.K. DNAform, Biotech company in 2002.
Dr Lezhava’s research interest is in Translational research, Molecular Diagnostics, Genomics technology development and he has published as many as 54 research papers, holds 4 patents and 11 technical disclosures. For his outstanding contributions to research, Dr Lezhava has received the Suzuken Memorial Foundation award in 2007 and Letter of Appreciation from President of RIKEN in 2009.
Dr Lezhava graduated with a PhD from the Hiroshima University, Faculty of Engineering, Department of Fermentation Technology and Master of Science from Tbilisi State University, Faculty of Biology, Department of Genetics, in 1996 and 1990 respectively. His philosophy is “Professionalism of the Group is a key for successful activities”. Therefore as a group leader and a Program Director his task is to attract motivated individuals with a strong background from both, industry and academia.
SINGAPORE, 7 July 2022 – MiRXES Pte Ltd, a Singapore-headquartered biotechnology company, whose mission is to save and improve lives through early, actionable, and personalized diagnoses with its innovative RNA-powered cancer early detection solutions, announced today the signing of a Memorandum of Understanding (MOU) that launched Project CADENCE (CAncer Detected Early caN be CurEd). Project CADENCE is the world’s first large-scale clinical research project for the discovery and validation of novel combinations blood-borne circulating microRNA (miRNA) and DNA methylation biomarkers that will lead to the development of a multi-cancer early detection test for up to nine high incidence and high mortality cancers, including lung, breast, colorectal, liver, stomach (gastric), esophageal, ovarian, pancreatic, and prostate cancers.
A new national consortium – the Consortium for Clinical Research and Innovation, Singapore (CRIS) – has been officially launched by the Minister for Health Mr Ong Ye Kung on 6 April 2022 CRIS brings together five key national R&D, clinical translation and service initiatives that will advance clinical research and innovation for Singapore, and establish important capabilities for a future-ready healthcare system